Originally Posted by
rich
Sickle cell anemia is not an infectious disease.
It is a chronic condition, although in a significant section of the population it can become a killer. It is handed down genetically like certain forms of breast cancer.
Sickle cell anemia is overwhelmingly a condition found in Africans.
Why should people in Africa have such a preponderance of the sickle cell gene? I gather it might confer some sort of protection from malaria but dont quote me on that.
Rich, you are quite right about sickle cell being beneficial when it comes to malaria. I’m not certain exactly how it works but the sickle shape of the blood cell, I think it is the red cells, because it is an unusual shape prevents the particular mechanism causing malaria to take place.
I understand it is also quite common in people from the Indian Sub-continent for the same reason. Obviously people who cannot get malaria are more likely to survive than those who can and therefore are likely to die from the disease. Those who are protected by sickle cell are going to be more likely to pass the gene which causes it on to their children, only a certain proportion of which will inherit the gene. Like so many other such traits whether a child has sickle cell is down to pot luck. Parents could have three or four children, none of who have sickle cell or they could have only two and both inherit it.
I don’t know if there are any tests to check if a foetus has sickle cell as there are for other genetic illnesses but if there still isn’t then it’s long past time when great efforts were made to find one because I understand the condition can be quite debilitating and at times extemely painful.
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